Description : |
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
85.6 kDa |
AA Sequence : |
MKETDREAVATAVQRVAGMLQRPDQ LDKVEQYRRREARKKASVEARLKAA IQSQLDGVRTGLSQLHNALNDVKDI QQSLADVSKDWRQSINTIESLKDVK DAVVQHSQLAAAVENLKNIFSVPEI VRETQDLIEQGALLQAHRKLMDLEC SRDGLMYEQYRMDSGNTRDMTLIHG YFGSTQGLSDELAKQLWMVLQRSLV TVRRDPTLLVSVVRIIEREEKIDRR ILDRKKQTGFVPPGRPKNWKEKMFT ILERTVTTRIEGTQADTRESDKMWL VRHLEIIRKYVLDDLIVAKNLMVQC FPPHYEIFKNLLNMYHQALSTRMQD LASEDLEANEIVSLLTWVLNTYTST EMMRNVELAPEVDVGTLEPLLSPHV VSELLDTYMSTLTSNIIAWLRKALE TDKKDWVKETEPEADQDGYYQTTLP AIVFQMFEQNLQVAAQISEDLKTKV LVLCLQQMNSFLSRYKDEAQLYKEE HLRNRQHPHCYVQYMIAIINNCQTF KESIVSLKRKYLKNEVEEGVSPSQP SMDGILDAIAKEGCSGLLEEVFLDL EQHLNELMTKKWLLGSNAVDIICVT VEDYFNDFAKIKKPYKKRMTAEAHR RVVVEYLRAVMQKRISFRSPEERKE GAEKMVREAEQLRFLFRKLASGFGE DVDGYCDTIVAVAEVIKLTDPSLLY LEVSTLVSKYPDIRDDHIGALLAVR GDASRDMKQTIMETLEQGPAQASPS YVPLFKDIVVPSLNVAKLLKSGPTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |