Recombinant Human EXTL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EXTL1-2684H
• Product Overview: EXTL1 MS Standard C13 and N15-labeled recombinant protein (NP_004446) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 74.7 kDa
• AA Sequence: MQSWRRRKSLWLALSASWLLLVLLG GFSLLRLALPPRPRPGASQGWPRWL DAELLQSFSQPGELPEDAVSPPQAP HGGSCNWESCFDTSKCRGDGLKVFV YPAVGTISETHRRILASIEGSRFYT FSPAGACLLLLLSLDAQTGECSSMP LQWNRGRNHLVLRLHPAPCPRTFQL GQAMVAEASPTVDSFRPGFDVALPF LPEAHPLRGGAPGQLRQHSPQPGVA LLALEEERGGWRTADTGSSACPWDG RCEQDPGPGQTQRQETLPNATFCLI SGHRPEAASRFLQALQAGCIPVLLS PRWELPFSEVIDWTKAAIVADERLP LQVLAALQEMSPARVLALRQQTQFL WDAYFSSVEKVIHTTLEVIQDRIFG TSAHPSLLWNSPPGALLALSTFSTS PQDFPFYYLQQGSRPEGRFSALIWV GPPGQPPLKLIQAVAGSQHCAQILV LWSNERPLPSRWPETAVPLTVIDGH RKVSDRFYPYSTIRTDAILSLDARS SLSTSEVDFAFLVWQSFPERMVGFL TSSHFWDEAHGGWGYTAERTNEFSM VLTTAAFYHRYYHTLFTHSLPKALR TLADEAPTCVDVLMNFIVAAVTKLP PIKVPYGKQRQEAAPLAPGGPGPRP KPPAPAPDCINQIAAAFGHMPLLSS RLRLDPVLFKDPVSVQRKKYRSLEK PTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EXTL1 exostosin like glycosyltransferase 1 [ Homo sapiens (human) ]
• Official Symbol: EXTL1
• Synonyms: exostoses (multiple)-like 1; 3515; Ensembl:ENSG00000158008; MGC70794; exostosin-like 1;exostosin-L;multiple exostosis-like protein;alpha-N-acetylglucosaminyltransferase II;glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N- acetylglucosaminyltransferase;glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase; 2.4.1.224; EXTL
• Gene ID: 2134
• mRNA Refseq: NM_004455
• Protein Refseq: NP_004446
• MIM: 601738
• UniProt ID: Q92935