Recombinant Human F2 Protein, GST-tagged
Cat.No. : | F2-3610H |
Product Overview : | Human F2 full-length ORF ( NP_000497.1, 1 a.a. - 622 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 96.4 kDa |
AA Sequence : | MAHVRGLQLPGCLALAALCSLVHSQ HVFLAPQQARSLLQRVRRANTFLEE VRKGNLERECVEETCSYEEAFEALE SSTATDVFWAKYTACETARTPRDKL AACLEGNCAEGLGTNYRGHVNITRS GIECQLWRSRYPHKPEINSTTHPGA DLQENFCRNPDSSTTGPWCYTTDPT VRRQECSIPVCGQDQVTVAMTPRSE GSSVNLSPPLEQCVPDRGQQYQGRL AVTTHGLPCLAWASAQAKALSKHQD FNSAVQLVENFCRNPDGDEEGVWCY VAGKPGDFGYCDLNYCEEAVEEETG DGLDEDSDRAIEGRTATSEYQTFFN PRTFGSGEADCGLRPLFEKKSLEDK TERELLESYIDGRIVEGSDAEIGMS PWQVMLFRKSPQELLCGASLISDRW VLTAAHCLLYPPWDKNFTENDLLVR IGKHSRTRYERNIEKISMLEKIYIH PRYNWRENLDRDIALMKLKKPVAFS DYIHPVCLPDRETAASLLQAGYKGR VTGWGNLKETWTANVGKGQPSVLQV VNLPIVERPVCKDSTRIRITDNMFC AGYKPDEGKRGDACEGDSGGPFVMK SPFNNRWYQMGIVSWGEGCDRDGKY GFYTHVFRLKKWIQKVIDQFGE |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | F2 coagulation factor II (thrombin) [ Homo sapiens ] |
Official Symbol : | F2 |
Synonyms : | F2; coagulation factor II (thrombin); prothrombin; serine protease; prothrombin B-chain; PT; THPH1; |
Gene ID : | 2147 |
mRNA Refseq : | NM_000506 |
Protein Refseq : | NP_000497 |
MIM : | 176930 |
UniProt ID : | P00734 |
Products Types
◆ Native Protein | ||
F2-303R | Native Rat Thrombin | +Inquiry |
F2-1882H | Native Human Coagulation Factor II | +Inquiry |
F2-90B | Active Native Bovine Thrombin | +Inquiry |
◆ Lysates | ||
F2-2124MCL | Recombinant Mouse F2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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