Recombinant Human FABP1, GST-tagged
Cat.No. : | FABP1-12630H |
Product Overview : | Recombinant Human FABP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-127a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | FABP1 fatty acid binding protein 1, liver [ Homo sapiens ] |
Official Symbol : | FABP1 |
Synonyms : | FABP1; fatty acid binding protein 1, liver; fatty acid-binding protein, liver; L FABP; fatty acid-binding protein 1; liver-type fatty acid-binding protein; FABPL; L-FABP; |
Gene ID : | 2168 |
mRNA Refseq : | NM_001443 |
Protein Refseq : | NP_001434 |
MIM : | 134650 |
UniProt ID : | P07148 |
Chromosome Location : | 2p11 |
Pathway : | Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem; |
Function : | bile acid binding; chromatin binding; drug binding; fatty acid binding; long-chain fatty acid transporter activity; phospholipid binding; transporter activity; |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionElevated levels of FABP1 are associated with metabolic disorders like obesity and insulin resistance, making it a potential indicator for these conditions.
FABP1 binds to fatty acids, facilitating their transport and metabolism within liver cells.
While predominantly found in the liver, FABP1 is also expressed in the small intestine and kidney.
Yes, elevated FABP1 levels in blood or urine may indicate early stages of liver damage, enabling early intervention.
Genetic variations may contribute to differences in FABP1 expression, impacting an individual's susceptibility to certain diseases.
Customer Reviews (3)
Write a reviewOne notable advantage of using the FABP1 protein is the outstanding technical support provided by its manufacturer.
Its purity and functionality have been extensively tested, ensuring reliable and reproducible results in my research.
The knowledgeable and responsive support team offers valuable assistance and expertise, making troubleshooting and problem-solving much more efficient.
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