Recombinant Human FABP1 Protein (Ser2-Ile127), His tagged

• Cat.No.: FABP1-2971H
• Product Overview: Recombinant human FABP1 (Ser2-Ile127) protein fused with His tag was expressed in E. coli.

Specification

• Description: Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 14.8 kDa
• Protein Length: Ser2-Ile127
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: FABP1 fatty acid binding protein 1, liver [ Homo sapiens (human) ]
• Official Symbol: FABP1
• Synonyms: FABP1; fatty acid binding protein 1, liver; fatty acid-binding protein, liver; L FABP; fatty acid-binding protein 1; liver-type fatty acid-binding protein; FABPL; L-FABP
• Gene ID: 2168
• mRNA Refseq: NM_001443
• Protein Refseq: NP_001434
• MIM: 134650
• UniProt ID: P07148

Reviews

07/24/2019

One notable advantage of using the FABP1 protein is the outstanding technical support provided by its manufacturer.

05/28/2019

Its purity and functionality have been extensively tested, ensuring reliable and reproducible results in my research.

05/22/2019

The knowledgeable and responsive support team offers valuable assistance and expertise, making troubleshooting and problem-solving much more efficient.

Q&As

How is FABP1 linked to metabolic disorders?

Elevated levels of FABP1 are associated with metabolic disorders like obesity and insulin resistance, making it a potential indicator for these conditions.

How is FABP1 involved in fatty acid metabolism?

FABP1 binds to fatty acids, facilitating their transport and metabolism within liver cells.

Are there other organs where FABP1 is expressed?

While predominantly found in the liver, FABP1 is also expressed in the small intestine and kidney.

Can FABP1 be used for early detection of liver damage?

Yes, elevated FABP1 levels in blood or urine may indicate early stages of liver damage, enabling early intervention.

Are there genetic variations influencing FABP1 expression?

Genetic variations may contribute to differences in FABP1 expression, impacting an individual's susceptibility to certain diseases.