Recombinant Human FABP5, GST-tagged
Cat.No. : | FABP5-12635H |
Product Overview : | Recombinant Human FABP5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-135a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | FABP5 fatty acid binding protein 5 (psoriasis-associated) [ Homo sapiens ] |
Official Symbol : | FABP5 |
Synonyms : | FABP5; fatty acid binding protein 5 (psoriasis-associated); fatty acid-binding protein, epidermal; E FABP; KFABP; PA FABP; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog; EFABP; E-FABP; PAFABP; PA-FABP; |
Gene ID : | 2171 |
mRNA Refseq : | NM_001444 |
Protein Refseq : | NP_001435 |
MIM : | 605168 |
UniProt ID : | Q01469 |
Chromosome Location : | 8q21.13 |
Pathway : | PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem; |
Function : | fatty acid binding; lipid binding; protein binding; transporter activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDysregulation or abnormal expression of FABP5 is associated with conditions such as cancer, metabolic disorders, and inflammatory diseases.
Fatty Acid-Binding Protein 5 (FABP5) functions in cellular processes, primarily playing a role in lipid metabolism and fatty acid transport.
FABP5 contributes to the regulation of lipid homeostasis and inflammatory responses in cells, linking lipid metabolism to immune function.
There are potential therapeutic implications related to FABP5 in diseases involving lipid metabolism and inflammation, making it a target for drug development.
FABP5 participates in the binding and transport of fatty acids within cells, facilitating their intracellular trafficking.
FABP5 is predominantly localized in the cytoplasm of cells, where it binds and transports fatty acids.
FABP5 preferentially interacts with long-chain fatty acids, influencing its cellular functions related to lipid metabolism.
Customer Reviews (3)
Write a reviewThe product's rapid action in triggering cellular responses significantly expedited our experiments.
Precise immunoprecipitation results consistently reflected the product's quality.
Replicating outcomes across diverse cell lines underscored the product's consistent behavior.
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