Recombinant Human FABP5 protein, His-tagged

• Cat.No.: FABP5-366H
• Product Overview: Recombinant Human FABP5 protein (Ala2-Glu135), fused to His tag at N-terminus, was expressed in E.coli.

Specification

• Description: Fatty acid-binding protein 5 (FABP5), is also known as Fatty acid-binding protein, epidermal (E-FABP), Psoriasis-associated fatty acid-binding protein homolog (PA-FABP). FABP5/E-FABP belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. FABP5/E-FABP is highly expressed in psoriatic skin. FABP5/E-FABP has high specificity for fatty acids and has highest affinity for C18 chain length. FABP5 may be involved in keratinocyte differentiation.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 16 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
• Protein length: 134
• Endotoxin: Less than 1.0 EU per ug by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 centigrade to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: FABP5
• Official Symbol: FABP5
• Synonyms: FABP5; fatty acid binding protein 5 (psoriasis-associated); fatty acid-binding protein, epidermal; E FABP; KFABP; PA FABP; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog; EFABP; E-FABP; PAFABP; PA-FABP
• Gene ID: 2171
• mRNA Refseq: NM_001444
• Protein Refseq: NP_001435
• MIM: 605168
• UniProt ID: Q01469

Reviews

06/12/2020

The product's rapid action in triggering cellular responses significantly expedited our experiments.

12/15/2018

Precise immunoprecipitation results consistently reflected the product's quality.

05/05/2016

Replicating outcomes across diverse cell lines underscored the product's consistent behavior.

Q&As

What diseases or conditions are associated with dysregulation or abnormal expression of FABP5?

Dysregulation or abnormal expression of FABP5 is associated with conditions such as cancer, metabolic disorders, and inflammatory diseases.

What is the primary function of Fatty Acid-Binding Protein 5 (FABP5) in cellular processes and lipid metabolism?

Fatty Acid-Binding Protein 5 (FABP5) functions in cellular processes, primarily playing a role in lipid metabolism and fatty acid transport.

How does FABP5 contribute to the regulation of lipid homeostasis and inflammatory responses in cells?

FABP5 contributes to the regulation of lipid homeostasis and inflammatory responses in cells, linking lipid metabolism to immune function.

Are there therapeutic implications or potential targets related to FABP5 in diseases involving lipid metabolism and inflammation?

There are potential therapeutic implications related to FABP5 in diseases involving lipid metabolism and inflammation, making it a target for drug development.

How does FABP5 participate in the binding and transport of fatty acids within cells?

FABP5 participates in the binding and transport of fatty acids within cells, facilitating their intracellular trafficking.

In which cellular compartments is FABP5 predominantly localized?

FABP5 is predominantly localized in the cytoplasm of cells, where it binds and transports fatty acids.

Are there specific types of fatty acids that FABP5 preferentially interacts with, influencing its cellular functions?

FABP5 preferentially interacts with long-chain fatty acids, influencing its cellular functions related to lipid metabolism.