Recombinant Human FBXO6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FBXO6-544H
• Product Overview: FBXO6 MS Standard C13 and N15-labeled recombinant protein (NP_060908) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 33.9 kDa
• AA Sequence: MDAPHSKAALDSINELPENILLELF THVPARQLLLNCRLVCSLWRDLIDL MTLWKRKCLREGFITKDWDQPVADW KIFYFLRSLHRNLLRNPCAEEDMFA WQIDFNGGDRWKVESLPGAHGTDFP DPKVKKYFVTSYEMCLKSQLVDLVA EGYWEELLDTFRPDIVVKDWFAARA DCGCTYQLKVQLASADYFVLASFEP PPVTIQQWNNATWTEVSYTFSDYPR GVRYILFQHGGRDTQYWAGWYGPRV TNSSIVVSPKMTRNQASSEAQPGQK HGQEEAAQSPYRAVVQIFTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FBXO6 F-box protein 6 [ Homo sapiens (human) ]
• Official Symbol: FBXO6
• Synonyms: FBXO6; F-box protein 6; F box only protein 6; F-box only protein 6; FBG2; FBS2; FBX6; Fbx6b; F-box protein FBG2; F-box protein Fbx6; F-box/G-domain protein 2; F-box protein that recognizes sugar chains 2
• Gene ID: 26270
• mRNA Refseq: NM_018438
• Protein Refseq: NP_060908
• MIM: 605647
• UniProt ID: Q9NRD1