Recombinant Human FBXW12 Protein, GST-tagged
| Cat.No. : | FBXW12-3968H |
| Product Overview : | Human FBXW12 full-length ORF ( AAI01306.1, 1 a.a. - 445 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
| Description : | Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
| Source : | Wheat Germ |
| Species : | Human |
| Tag : | GST |
| Molecular Mass : | 77.2 kDa |
| AA Sequence : | MSPTHQIQDPKHWNRIADSDYLWRS LSLQRWDCSNFTNQHLGTHTWKQFF LHQRRKELRLALAQPHNFIYKVTKN IAFETELAYLSGNRLTVDEQEKSII CSVSPKQELCAWDVQEGTMIWSSPV QEFHFSNLVTLPQMHLAITMDRKKT IKVWNCQDRDALAVLPMPQPCYCME AYLTKDGPFLMVGDAAGDIYTFTLP GLRDVSKVTAFQYGIVLLHCSPDKK WVFACGTYSRTLPQVFLTESLLRPS EGSDPLSTLLPHKLCASACWTPKVK NRITLMSQSSTGKKTEFITFDLTTK KTGGQTVIQAYEIASFQVAAHLKCP IWMGASDGYMIVFTSGPYLLLFSIT GFLLQRFEDHQAAINNFWVDPCYVL TTSENSVHVYMWEEGGRHPYLRSCC HLENTWHDHTTDSCISSVMCDNASI VLRVRKVSDSSILVMYSLNT |
| Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
| Notes : | Best use within three months from the date of receipt of this protein. |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Gene Name : | FBXW12 F-box and WD repeat domain containing 12 [ Homo sapiens ] |
| Official Symbol : | FBXW12 |
| Synonyms : | FBXW12; F-box and WD repeat domain containing 12; F box and WD 40 domain protein 12 , F box only protein 35 , FBXO35; F-box/WD repeat-containing protein 12; Fbw12; F-box only protein 35; F-box and WD-40 domain protein 12; F-box- and WD40-repeat-containing protein; F-box and WD-40 domain-containing protein 12; FBW12; FBXO12; FBXO35; MGC120385; MGC120386; MGC120387; |
| Gene ID : | 285231 |
| mRNA Refseq : | NM_001159927 |
| Protein Refseq : | NP_001153399 |
| MIM : | 609075 |
| UniProt ID : | Q6X9E4 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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