| Description : |
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
30.6 kDa |
| AA Sequence : |
MVGVGGGDVEDVTPRPGGCQISGRG ARGCNGIPGAAAWEAALPRRRPRRH PSVNPRSRAAGSPRTRGRRTEERPS GSRLGDRGRGRALPGGRLGGRGRGR APERVGGRGRGRGTAAPRAAPAARG SRPGPAGTMAAGSITTLPALPEDGG SGAFPPGHFKDPKRLYCKNGGFFLR IHPDGRVDGVREKSDPHIKLQLQAE ERGVVSIKGVCANRYLAMKEDGRLL ASKCVTDECFFFERLESNNYNTYRS RKYTSWYVALKRTGQYKLGSKTGPG QKAILFLPMSAKSTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
