| Description : |
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His-Avi |
| Form : |
Supplied as 0.22um filtered solution in PBS (pH 7.4). |
| Molecular Mass : |
The protein has a predicted MW of 42 KDa. Due to glycosylation, the protein migrates to 68-80 KDa based on Bis-Tris PAGE result. |
| Protein length : |
It contains Arg22-Glu374. |
| Endotoxin : |
Less than 0.05 EU per ug by the LAL method. |
| Purity : |
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Storage : |
The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
| Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
