Recombinant Human FGFR4 Protein (22-369aa), C-His tagged
Cat.No. : | FGFR4-5420H |
Product Overview : | Recombinant human FGFR4 (22-369aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. |
Source : | Baculovirus |
Species : | Human |
Tag : | C-His |
Form : | Liquid |
Molecular Mass : | 39.5 kDa (356aa) |
Protein Length : | 22-369aa |
AA Sequence : | LEASEEVELEPCLAPSLEQQEQELT VALGQPVRLCCGRAERGGHWYKEGS RLAPAGRVRGWRGRLEIASFLPEDA GRYLCLARGSMIVLQNLTLITGDSL TSSNDDEDPKSHRDPSNRHSYPQQA PYWTHPQRMEKKLHAVPAGNTVKFR CPAAGNPTPTIRWLKDGQAFHGENR IGGIRLRHQHWSLVMESVVPSDRGT YTCLVENAVGSIRYNYLLDVLERSP HRPILQAGLPANTTAVVGSDVELLC KVYSDAQPHIQWLKHIVINGSSFGA DGFPYVQVLKTADINSSEVEVLYLR NVSAEDAGEYTCLAGNSIGLSYQSA WLTVLPEEDPTWTAAAPEARYTDLE HHHHHH |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 90% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/mL (determined by absorbance at 280nm) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | FGFR4 fibroblast growth factor receptor 4 [ Homo sapiens (human) ] |
Official Symbol : | FGFR4 |
Synonyms : | FGFR4; fibroblast growth factor receptor 4; CD334; JTK2; FGFR-4; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; tyrosine kinase related to fibroblast growth factor receptor; TKF; MGC20292; |
Gene ID : | 2264 |
mRNA Refseq : | NM_002011 |
Protein Refseq : | NP_002002 |
MIM : | 134935 |
UniProt ID : | P22455 |
Products Types
◆ Recombinant Protein | ||
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FGFR4-4143H | Recombinant Human FGFR4 Protein, GST-tagged | +Inquiry |
FGFR4-1996R | Recombinant Rat FGFR4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FGFR4-1516RCL | Recombinant Rat FGFR4 cell lysate | +Inquiry |
FGFR4-2757MCL | Recombinant Mouse FGFR4 cell lysate | +Inquiry |
FGFR4-1907HCL | Recombinant Human FGFR4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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