Recombinant Human Fibroblast Growth Factor 2 (basic) (aa 146)
Cat.No. : | FGF2-678H |
Product Overview : | Recombinant humanFibroblast Growth Factor 2 contains 146 amino acids. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FGF2-678H |
Description : | FGF2 hasbeen hypothesized that, during both wound healing of normal tissues and tumordevelopment, the action of heparan sulfate-degrading enzymes activates bFGF,thus mediating the formation of new blood vessels, a process known asangiogenesis. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a0.2 um sterile filtered solution, carrier free. |
Purity : | >95% asdetermined by SDS-PAGE analysis. |
Molecular Weight : | 17 kDa |
Endotoxin Level : | <0.1 ng/ug ofFGF2 |
Biological Activity : | Determined by thedose-dependent proliferation of BALB/3T3 cells. The EDSO range is 0.1-1.0ng/ml. |
Specific Activity : | 1.0 x 107to 1.0 x 106 units/mg |
Amino Acid Sequence : | PALPEDGGSGIKLQLQAEERNNYNT YRSRK AFPPGHFKDPGWSIKGVCAYTSWYV ALKRKRLYCKNGGFNRYLAMKEDGT GQYKLG SKT FLR旧PDGRV RLLASKCVTDGPGQKAILFL DGVREKSDPHECFFFELESPMSAKS |
Reconstitution : | Centrifuge vialprior to opening. Add sterile distilled water to the vial to fully solubilizethe protein to a concentration of 0.1-0.5 mg/ml. Further dilutions should bemade in medium or buffered solution containing carrier protein such as PBSwith 0.1%BSA. Please note that the addition of any carrier protein into thisproduct may produceunwanted endotoxin.This depends upon the particular application employed. |
Storage : | Store at -20°C to-80°C with a carrier protein (0.1%HSA or BSA) as a stabilizer for long termstorage. Please note that the addition of any carrier protein into thisproduct may produce unwanted endotoxin. This depends upon the particularapplication employed. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | FGF2 |
Gene Name : | FGF2 fibroblast growth factor 2(basic) [ Homo sapiens ] |
Synonyms : | FGF2; fibroblastgrowth factor 2 (basic); BFGF; FGFB; HBGF-2; heparin-binding growth factor 2; prostatropin;OTTHUMP00000037513; basic fibroblast growth factor bFGF |
Gene ID : | 2247 |
mRNA Refseq : | NM_002006 |
Protein Refseq : | NP_001997 |
MIM : | 134920 |
UniProt ID : | P09038 |
Chromosome Location : | 4q26 |
Pathway : | Angiopoietinreceptor Tie2-mediated signaling; Downstreamsignaling of activated FGFR; EndochondralOssification; FGFR ligand binding andactivation; FGFR1 ligand binding andactivation; FGFR1b ligand binding andactivation; FRS2-mediated cascade;Glypican 1 network; IRS-mediated signalling; IRS-related events; Integrins in angiogenesis; MAPKsignaling pathway; Melanoma; PI-3K cascade; PI3KCascade |
Function : | chemoattractantactivity; cytokine activity; fibroblast growth factor binding; fibroblast growthfactor receptor binding; growth factor activity; heparin binding;ligand-dependent nuclear receptor transcription coactivator activity; proteinbinding; protein tyrosine kinase activity; voltage-gated calcium channelactivity |
Products Types
◆ Recombinant Protein | ||
FGF2-4387R | Recombinant Rabbit FGF2 Protein | +Inquiry |
FGF2-24H | Active Recombinant Human FGF2 Protein (Formulation II-Carrier-Lyophilized, 134-288, 154 amino acid) | +Inquiry |
FGF2-12B | Recombinant Bovine FGF2 Protein | +Inquiry |
FGF2-929P | Recombinant Pig FGF2 Protein, His-tagged | +Inquiry |
FGF2-18H | Active Recombinant Human FGF2 Protein (143-288aa), Non-tagged | +Inquiry |
◆ Native Protein | ||
FGF2-26551TH | Native Human FGF2 | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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