Recombinant Human FMR1 Mutant (I304N) Protein, Myc/DDK-tagged
Cat.No. : | FMR1-058H |
Product Overview : | Purified mutant recombinant protein of Human fragile X mental retardation 1 (FMR1), transcript variant ISO1, mutation at(I304N) with a Myc/DDK tag was expressed in HEK293 |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 71 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | > 50 μg/mL as determined by microplate Bradford method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | FMR1 FMRP translational regulator 1 [ Homo sapiens (human) ] |
Official Symbol : | FMR1 |
Synonyms : | FMR1; FMRP translational regulator 1; POF; FMRP; POF1; FRAXA; synaptic functional regulator FMR1; fragile X mental retardation 1; fragile X mental retardation protein 1; truncated FMRP |
Gene ID : | 2332 |
mRNA Refseq : | NM_002024 |
Protein Refseq : | NP_002015 |
MIM : | 309550 |
UniProt ID : | Q06787 |
Products Types
◆ Recombinant Protein | ||
FMR1-4396H | Recombinant Human FMR1 Protein, GST-tagged | +Inquiry |
Fmr1-3058M | Recombinant Mouse Fmr1 Protein, Myc/DDK-tagged | +Inquiry |
FMR1-2028R | Recombinant Rat FMR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FMR1-12948H | Recombinant Human FMR1, GST-tagged | +Inquiry |
FMR1-2874H | Recombinant Human FMR1 Protein (Met1-Gly294), N-His tagged | +Inquiry |
◆ Lysates | ||
FMR1-6179HCL | Recombinant Human FMR1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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