Recombinant Human FN3KRP Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FN3KRP-3186H
• Product Overview: FN3KRP MS Standard C13 and N15-labeled recombinant protein (NP_078895) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34.4 kDa
• AA Sequence: MEELLRRELGCSSVRATGHSGGGCI SQGRSYDTDQGRVFVKVNPKAEARR MFEGEMASLTAILKTNTVKVPKPIK VLDAPGGGSVLVMEHMDMRHLSSHA AKLGAQLADLHLDNKKLGEMRLKEA GTVGRGGGQEERPFVARFGFDVVTC CGYLPQVNDWQEDWVVFYARQRIQP QMDMVEKESGDREALQLWSALQLKI PDLFRDLEIIPALLHGDLWGGNVAE DSSGPVIFDPASFYGHSEYELAIAG MFGGFSSSFYSAYHGKIPKAPGFEK RLQLYQLFHYLNHWNHFGSGYRGSS LNIMRNLVKTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FN3KRP fructosamine 3 kinase related protein [ Homo sapiens (human) ]
• Official Symbol: FN3KRP
• Synonyms: FN3KRP; fructosamine 3 kinase related protein; ketosamine-3-kinase; FLJ12171; FN3KL; FN3K-RP; FN3K-related protein; fructosamine-3-kinase-related protein
• Gene ID: 79672
• mRNA Refseq: NM_024619
• Protein Refseq: NP_078895
• MIM: 611683
• UniProt ID: Q9HA64