Recombinant Human FNTA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FNTA-4306H
• Product Overview: FNTA MS Standard C13 and N15-labeled recombinant protein (NP_002018) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 44.4 kDa
• AA Sequence: MAATEGVGEAAQGGEPGQPAQPPPQ PHPPPPQQQHKEEMAAEAGEAVASP MDDGFVSLDSPSYVLYRDRAEWADI DPVPQNDGPNPVVQIIYSDKFRDVY DYFRAVLQRDERSERAFKLTRDAIE LNAANYTVWHFRRVLLKSLQKDLHE EMNYITAIIEEQPKNYQVWHHRRVL VEWLRDPSQELEFIADILNQDAKNY HAWQHRQWVIQEFKLWDNELQYVDQ LLKEDVRNNSVWNQRYFVISNTTGY NDRAVLEREVQYTLEMIKLVPHNES AWNYLKGILQDRGLSKYPNLLNQLL DLQPSHSSPYLIAFLVDIYEDMLEN QCDNKEDILNKALELCEILAKEKDT IRKEYWRYIGRSLQSKHSTENDSPT NVQQTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FNTA farnesyltransferase, CAAX box, alpha [ Homo sapiens (human) ]
• Official Symbol: FNTA
• Synonyms: FNTA; farnesyltransferase, CAAX box, alpha; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; FPTA; PGGT1A; protein prenyltransferase alpha subunit repeat containing 2; PTAR2; FTase-alpha; GGTase-I-alpha; farnesyl-protein transferase alpha-subunit; ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase alpha subunit; MGC99680
• Gene ID: 2339
• mRNA Refseq: NM_002027
• Protein Refseq: NP_002018
• MIM: 134635
• UniProt ID: P49354