Recombinant Human FUCA2

• Cat.No.: FUCA2-28957TH
• Product Overview: Recombinant full length Human FUCA2 with N-terminal proprietary tag. Predicted MW 77.44 kDa.

Specification

• Description: This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells.
• Protein length: 467 amino acids
• Molecular Weight: 77.440kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MRPQELPRLAFPLLLLLLLLLPPPPCPAHSATRFDPTWES LDARQLPAWFDQAKFGIFIHWGVFSVPSFGSEWFWWYWQK EKIPKYVEFMKDNYPPSFKYEDFGPLFTAKFFNANQWADI FQASGAKYIVLTSKHHEGFTLWGSEYSWNWNAIDEGPKRD IVKELEVAIRNRTDLRFGLYYSLFEWFHPLFLEDESSSFH KRQFPVSKTLPELYELVNNYQPEVLWSDGDGGAPDQYWNS TGFLAWLYNESPVRGTVVTNDRWGAGSICKHGGFYTCSDR YNPGHLLPHKWENCMTIDKLSWGYRREAGISDYLTIEELV KQLVETVSCGGNLLMNIGPTLDGTISVVFEERLRQVGSWL KVNGEAIYETYTWRSQNDTVTPDVWYTSKPKEKLVYAIFL KWPTSGQLFLGHPKAILGATEVKLLGHGQPLNWISLEQNG IMVELPQLTIHQMPCKWGWALALTNVI
• Sequence Similarities: Belongs to the glycosyl hydrolase 29 family.

Gene Information

• Gene Name: FUCA2 fucosidase, alpha-L- 2, plasma [ Homo sapiens ]
• Official Symbol: FUCA2
• Synonyms: FUCA2; fucosidase, alpha-L- 2, plasma; plasma alpha-L-fucosidase; dJ20N2.5; MGC1314
• Gene ID: 2519
• mRNA Refseq: NM_032020
• Protein Refseq: NP_114409
• MIM: 136820
• Uniprot ID: Q9BTY2
• Chromosome Location: 6q24
• Pathway: Other glycan degradation, organism-specific biosystem; Other glycan degradation, conserved biosystem
• Function: alpha-L-fucosidase activity; catalytic activity; cation binding; hydrolase activity, acting on glycosyl bonds