| Description : |
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
42.9 kDa |
| Protein Length : |
537 |
| AA Sequence : |
MAWRGAGPSVPGAPGGVGLSLGLLL QLLLLLGPARGFGDEEERRCDPIRI SMCQNLGYNVTKMPNLVGHELQTDA ELQLTTFTPLIQYGCSSQLQFFLCS VYVPMCTEKINIPIGPCGGMCLSVK RRCEPVLKEFGFAWPESLNCSKFPP QNDHNHMCMEGPGDEEVPLPHKTPI QPGEECHSVGTNSDQYIWVKRSLNC VLKCGYDAGLYSRSAKEFTDIWMAV WASLCFISTAFTVLTFLIDSSRFSY PERPIIFLSMCYNIYSIAYIVRLTV GRERISCDFEEAAEPVLIQEGLKNT GCAIIFLLMYFFGMASSIWWVILTL TWFLAAGLKWGHEAIEMHSSYFHIA AWAIPAVKTIVILIMRLVDADELTG LCYVGNQNLDALTGFVVAPLFTYLV IGTLFIAAGLVALFKIRSNLQKDGT KTDKLERLMVKIGVFSVLYTVPATC VIACYFYEISNWALFRYSADDSNMA VEMLKIFMSLLVGITSGMWIWSAKT LHTWQKCSNRLVNSGKVKREKRGNG WVKPGKGSETVV |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
