Recombinant Human FZD7
Cat.No. : | FZD7-26288TH |
Product Overview : | Recombinant fragment of Human Frizzled 7 with a proprietary tag: predicted molecular weight 36.52 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. |
Protein length : | 99 amino acids |
Molecular Weight : | 36.520kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | High expression in adult skeletal muscle and fetal kidney, followed by fetal lung, adult heart, brain, and placenta. Specifically expressed in squamous cell esophageal carcinomas. |
Biological activity : | This product is useful for Antibody Production and Protein Array |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | GAGEICVGQNTSDGSGGPGGGPTAY PTAPYLPDLPFTALPPGASDGRGRP AFPFSCPRQLKVPPYLGYRFLGERD CGAPCEPGRANGLMYFKEEERRFA |
Sequence Similarities : | Belongs to the G-protein coupled receptor Fz/Smo family.Contains 1 FZ (frizzled) domain. |
Gene Name : | FZD7 frizzled family receptor 7 [ Homo sapiens ] |
Official Symbol : | FZD7 |
Synonyms : | FZD7; frizzled family receptor 7; frizzled (Drosophila) homolog 7 , frizzled 7, seven transmembrane spanning receptor , frizzled homolog 7 (Drosophila); frizzled-7; FzE3; |
Gene ID : | 8324 |
mRNA Refseq : | NM_003507 |
Protein Refseq : | NP_003498 |
MIM : | 603410 |
Uniprot ID : | O75084 |
Chromosome Location : | 2q33 |
Pathway : | Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; |
Function : | G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; receptor activity; |
Products Types
◆ Recombinant Protein | ||
FZD7-258H | Recombinant Human FZD7 Protein, Fc-tagged | +Inquiry |
FZD7-2166H | Recombinant Human FZD7 Protein, GST-tagged | +Inquiry |
FZD7-4598H | Recombinant Human FZD7 Protein, GST-tagged | +Inquiry |
Fzd7-54M | Recombinant Mouse Fzd7 Protein, His (Fc)-Avi-tagged | +Inquiry |
FZD7-1113HFL | Recombinant Human FZD7 protein, His&Flag-tagged | +Inquiry |
◆ Lysates | ||
FZD7-6088HCL | Recombinant Human FZD7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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