Recombinant Human G Protein-Coupled Receptor Kinase 7, GST-tagged
Cat.No. : | GRK7-1021H |
Product Overview : | Full-length recombinant human GRK7 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | GRK7-1021H |
Description : | GRK7 is a member of the G protein-coupled receptor kinase subfamily and is a Ser/Thr protein kinase. GRK7 is specifically expressed in the retina and has been shown to phosphorylate cone opsins and initiate their deactivation. GRK7 catalyzes rhodopsin phosphorylation in a light-dependent manner. GRK7 co-localizes with GRK1 in human cone outer segments. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 89 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Purity : | >95% |
Concentration : | 0.1 ug/ul |
Specific Activity : | 2.5 nmol/min/mg |
Sequences : | Full length |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Chemokine signaling pathway; Endocytosis; Phototransduction; Visual signal transduction: Cones |
Gene Name : | GRK7 G protein-coupled receptor kinase 7 [ Homo sapiens ] |
Official Symbol : | GRK7 |
Synonyms : | GRK7; G protein-coupled receptor kinase 7; GPRK7; G protein-coupled receptor kinase 7; OTTHUMP00000214002; g protein-coupled receptor kinase GRK7 |
Gene ID : | 131890 |
mRNA Refseq : | NM_139209 |
Protein Refseq : | NP_631948 |
MIM : | 606987 |
UniProt ID : | Q8WTQ7 |
Chromosome Location : | 3q24 |
Function : | ATP binding; G-protein coupled receptor kinase activity; nucleotide binding; rhodopsin kinase activity; signal transducer activity |
Products Types
◆ Recombinant Protein | ||
GRK7-147H | Recombinant Human GRK7 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
GRK7-5361H | Recombinant Human GRK7 Protein, GST-tagged | +Inquiry |
GRK7-5360H | Active Recombinant Human GRK7 Protein, GST-tagged | +Inquiry |
GRK7-2357H | Recombinant Human GRK7 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
GRK7-753HCL | Recombinant Human GRK7 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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