Recombinant Human GBA Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | GBA-5174H |
Product Overview : | GBA MS Standard C13 and N15-labeled recombinant protein (NP_001005741) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 59.7 kDa |
AA Sequence : | MEFSSPSREECPKPLSRVSIMAGSL TGLLLLQAVSWASGARPCIPKSFGY SSVVCVCNATYCDSFDPPTFPALGT FSRYESTRSGRRMELSMGPIQANHT GTGLLLTLQPEQKFQKVKGFGGAMT DAAALNILALSPPAQNLLLKSYFSE EGIGYNIIRVPMASCDFSIRTYTYA DTPDDFQLHNFSLPEEDTKLKIPLI HRALQLAQRPVSLLASPWTSPTWLK TNGAVNGKGSLKGQPGDIYHQTWAR YFVKFLDAYAEHKLQFWAVTAENEP SAGLLSGYPFQCLGFTPEHQRDFIA RDLGPTLANSTHHNVRLLMLDDQRL LLPHWAKVVLTDPEAAKYVHGIAVH WYLDFLAPAKATLGETHRLFPNTML FASEACVGSKFWEQSVRLGSWDRGM QYSHSIITNLLYHVVGWTDWNLALN PEGGPNWVRNFVDSPIIVDITKDTF YKQPMFYHLGHFSKFIPEGSQRVGL VASQKNDLDAVALMHPDGSAVVVVL NRSSKDVPLTIKDPAVGFLETISPG YSIHTYLWRRQTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | GBA glucosylceramidase beta [ Homo sapiens (human) ] |
Official Symbol : | GBA |
Synonyms : | GBA; glucosidase, beta, acid; GLUC, glucosidase, beta; acid (includes glucosylceramidase), glucosylceramidase; glucosylceramidase; GBA1; alglucerase; imiglucerase; acid beta-glucosidase; beta-glucocerebrosidase; lysosomal glucocerebrosidase; D-glucosyl-N-acylsphingosine glucohydrolase; GCB; GLUC; |
Gene ID : | 2629 |
mRNA Refseq : | NM_001005741 |
Protein Refseq : | NP_001005741 |
MIM : | 606463 |
UniProt ID : | P04062 |
Products Types
◆ Recombinant Protein | ||
GBA-539H | Recombinant Human GBA Protein (Ala40-Gln536), His-tagged | +Inquiry |
GBA-3492M | Recombinant Mouse GBA Protein, His (Fc)-Avi-tagged | +Inquiry |
Gba-3165M | Recombinant Mouse Gba Protein, Myc/DDK-tagged | +Inquiry |
GBA-4764H | Recombinant Human GBA Protein, GST-tagged | +Inquiry |
GBA-2943H | Recombinant Human GBA protein, His-SUMO & Myc-tagged | +Inquiry |
◆ Lysates | ||
GBA-6002HCL | Recombinant Human GBA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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