Recombinant Human GBP1

• Cat.No.: GBP1-28991TH
• Product Overview: Recombinant full length Human GBP1 with N terminal proprietary tag; Predicted MWt 91.23 kDa.

Specification

• Description: Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.
• Protein length: 592 amino acids
• Molecular Weight: 91.230kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVV VAIVGLYRTGKSYLMNKLAGKKKGFSLGSTVQSHTKGIWM WCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDE NENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDE YLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTK TLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENAVLALA QIENSAAVQKAIAHYEQQMGQKVQLPTESLQELLDLHRDS EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQ EASSDRCSGLLQVIFSPLEEEVKAGIYSKPGGYRLFVQKL QDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQK ERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQL LKEGFQKESRIMKNEIQDLQTKMRRRKACTIS
• Sequence Similarities: Belongs to the GBP family.

Gene Information

• Gene Name: GBP1 guanylate binding protein 1, interferon-inducible [ Homo sapiens ]
• Official Symbol: GBP1
• Synonyms: GBP1; guanylate binding protein 1, interferon-inducible; guanylate binding protein 1, interferon inducible, 67kDa; interferon-induced guanylate-binding protein 1
• Gene ID: 2633
• mRNA Refseq: NM_002053
• Protein Refseq: NP_002044
• MIM: 600411
• Uniprot ID: P32455
• Chromosome Location: 1p22.2
• Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem; Type II interferon signaling (IFNG), organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding