Recombinant Human GCLC Protein, GST-tagged
Cat.No. : | GCLC-4800H |
Product Overview : | Human GCLC full-length ORF ( NP_001489.1, 1 a.a. - 637 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6. The regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 99.2 kDa |
AA Sequence : | MGLLSQGSPLSWEETKRHADHVRRH GILQFLHIYHAVKDRHKDVLKWGDE VEYMLVSFDHENKKVRLVLSGEKVL ETLQEKGERTNPNHPTLWRPEYGSY MIEGTPGQPYGGTMSEFNTVEANMR KRRKEATSILEENQALCTITSFPRL GCPGFTLPEVKPNPVEGGASKSLFF PDEAINKHPRFSTLTRNIRHRRGEK VVINVPIFKDKNTPSPFIETFTEDD EASRASKPDHIYMDAMGFGMGNCCL QVTFQACSISEARYLYDQLATICPI VMALSAASPFYRGYVSDIDCRWGVI SASVDDRTREERGLEPLKNNNYRIS KSRYDSIDSYLSKCGEKYNDIDLTI DKEIYEQLLQEGIDHLLAQHVAHLF IRDPLTLFEEKIHLDDANESDHFEN IQSTNWQTMRFKPPPPNSDIGWRVE FRPMEVQLTDFENSAYVVFVVLLTR VILSYKLDFLIPLSKVDENMKVAQK RDAVLQGMFYFRKDICKGGNAVVDG CGKAQNSTELAAEEYTLMSIDTIIN GKEGVFPGLIPILNSYLENMEVDVD TRCSILNYLKLIKKRASGELMTVAR WMREFIANHPDYKQDSVITDEMNYS LILKCNQIANELCECPELLGSAFRK VKYSGSKTDSSN |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GCLC glutamate-cysteine ligase, catalytic subunit [ Homo sapiens ] |
Official Symbol : | GCLC |
Synonyms : | GCLC; glutamate-cysteine ligase, catalytic subunit; GLCL, GLCLC; glutamate--cysteine ligase catalytic subunit; GCS; gamma-ECS; GCS heavy chain; gamma-glutamylcysteine synthetase; GCL; GLCL; GLCLC; |
Gene ID : | 2729 |
mRNA Refseq : | NM_001197115 |
Protein Refseq : | NP_001184044 |
MIM : | 606857 |
UniProt ID : | P48506 |
Products Types
◆ Recombinant Protein | ||
GCLC-2148R | Recombinant Rat GCLC Protein, His (Fc)-Avi-tagged | +Inquiry |
GCLC-3507M | Recombinant Mouse GCLC Protein, His (Fc)-Avi-tagged | +Inquiry |
GCLC-973H | Recombinant Human GCLC Protein, His (Fc)-Avi-tagged | +Inquiry |
GCLC-1643R | Recombinant Rhesus Macaque GCLC Protein, His (Fc)-Avi-tagged | +Inquiry |
GCLC-668H | Recombinant Human GCLC Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
GCLC-5983HCL | Recombinant Human GCLC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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