Recombinant Human GFER Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GFER-1412H
• Product Overview: GFER MS Standard C13 and N15-labeled recombinant protein (NP_005253) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 23.3 kDa
• AA Sequence: MAAPGERGRFHGGNLFFLPGGARSE MMDDLATDARGRGAGRRDAAASAST PAQAPTSDSPVAEDASRRRPCRACV DFKTWMRTQQKRDTKFREDCPPDRE ELGRHSWAVLHTLAAYYPDLPTPEQ QQDMAQFIHLFSKFYPCEECAEDLR KRLCRNHPDTRTRACFTQWLCHLHN EVNRKLGKPDFDCSKVDERWRDGWK DGSCDTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GFER growth factor, augmenter of liver regeneration [ Homo sapiens (human) ]
• Official Symbol: GFER
• Synonyms: GFER; growth factor, augmenter of liver regeneration; growth factor, erv1 (S. cerevisiae) like (augmenter of liver regeneration); FAD-linked sulfhydryl oxidase ALR; ALR; ERV1; ERV1 homolog (S. cerevisiae); HERV1; HPO1; HPO2; HSS; ERV1 homolog; hepatopoietin protein; erv1-like growth factor; hepatic regenerative stimulation substance; HPO
• Gene ID: 2671
• mRNA Refseq: NM_005262
• Protein Refseq: NP_005253
• MIM: 600924
• UniProt ID: P55789