| Description : |
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA. Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
86.2 kDa |
| AA Sequence : |
MLTNLRIFAMSHQTIPSVYINNICC YKIRASLKRLKPHVPLGRNCSSLPG LIGNDIKSIHSIINPPIAKIRNIGI MAHIDAGKTTTTERILYYSGYTRSL GDVDDGDTVTDFMAQERERGITIQS AAVTFDWKGYRVNLIDTPGHVDFTL EVERCLRVLDGAVAVFDASAGVEAQ TLTVWRQADKHNIPRICFLNKMDKT GASFKYAVESIREKLKAKPLLLQLP IGEAKTFKGVVDVVMKEKLLWNCNS NDGKDFERKPLLEMNDPELLKETTE ARNALIEQVADLDDEFADLVLEEFS ENFDLLPAEKLQTAIHRVTLAQTAV PVLCGSALKNKGIQPLLDAVTMYLP SPEERNYEFLQWYKDDLCALAFKVL HDKQRGPLVFMRIYSGTIKPQLAIH NINGNCTERISRLLLPFADQHVEIH SLTAGNIALTVGLKHTATGDTIVSS KSSALAAARRAEREGEKKHRQNNEA ERLLLAGVEIPEPVFFCTIEPPSLS KQPDLEHALKCLQREDPSLKVRLDP DSGQTVLCGMGELHIEIIHDRIKRE YGLETYLGPLQVAYRETILNSVRAT DTLDRTLGDKRHLVTVEVGARPIET SSVMPVIEYAESINEGLLKVSQEAI ENGIHSACLQGPLLGSPIQDVAITL HSLTIHPGTSTTMISACVSRCVQKA LKKADKQVLEPLMNLEVTVARDYLS PVLADLAQRRGNIQEIQTRQDNKVV IGFVPLAGIMGYSTVLRTLTSGSAT FALELSTYQAMNPQDQNTLLNRRSG LTTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
