Recombinant Human GLA Protein, His-tagged
Cat.No. : | GLA-174H |
Product Overview : | Recombinant Human GLA(Gly147~Ser371) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 31.4kDa |
Identity : | Reconstitute in PBS or others |
Protein length : | Gly147~Ser371 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | GLA galactosidase, alpha [ Homo sapiens ] |
Official Symbol : | GLA |
Synonyms : | GLA; galactosidase, alpha; alpha-galactosidase A; GALA; melibiase; alpha-gal A; agalsidase alfa; alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase 1; |
Gene ID : | 2717 |
mRNA Refseq : | NM_000169 |
Protein Refseq : | NP_000160 |
MIM : | 300644 |
UniProt ID : | P06280 |
Products Types
◆ Recombinant Protein | ||
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Gla-7408M | Active Recombinant Mouse Gla protein, His-tagged | +Inquiry |
GLA-45H | Active Recombinant Human GLA protein, His-tagged | +Inquiry |
GLA-173H | Recombinant Human GLA Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GLA-2173HCL | Recombinant Human GLA cell lysate | +Inquiry |
GLA-1521MCL | Recombinant Mouse GLA cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0869 | Alpha-Galactosidase Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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