Recombinant Human GLRX Protein, His-tagged
Cat.No. : | GLRX-139H |
Product Overview : | Active human recombinant N-terminal His-TEV tagged Grx1 (2-106) was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 13.9 kDa |
Purity : | ≥ 95% estimated by SDS-PAGE |
Unit Definition : | One unit is defined as the amount of enzyme required to produce 1 nmol of Eosin-GSH per minute at 25 centigrade in 0,1 Mpotassium phosphate, pH 7.5, containing 1 mM EDTA, 1U/mL glutathione reductase, 0.5 mM GSH, 0.25 mM NADPH, 0.75 μM alkylated BSA, and 20 μM Eosin-GS-BSA. |
Applications : | Enzyme Activity |
Stability : | ≥ 1 year |
Storage : | At -80 centigrade. |
Storage Buffer : | 50 mM Tris-HCl, pH 7.8, with 150 mM sodium chloride, 10% glycerol, 1 mM EDTA, and 0.1 mM DTT |
Gene Name : | GLRX glutaredoxin [ Homo sapiens (human) ] |
Official Symbol : | GLRX |
Synonyms : | GLRX; glutaredoxin; GRX; GRX1; glutaredoxin-1; TTase-1; thioltransferase; thioltransferase-1; EC 1.8.4.1; tyrosine-protein kinase Blk; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase; b lymphocyte kinase; p55-Blk; EC 2.7.10.2 |
Gene ID : | 2745 |
mRNA Refseq : | NM_002064 |
Protein Refseq : | NP_002055 |
MIM : | 600443 |
UniProt ID : | P35754 |
Products Types
◆ Recombinant Protein | ||
Glrx-631M | Recombinant Mouse Glrx Protein, His-tagged | +Inquiry |
GLRX-015H | Recombinant Human GLRX Protein | +Inquiry |
GLRX-154H | Recombinant Human GLRX Protein | +Inquiry |
GLRX-4975H | Recombinant Human GLRX Protein, GST-tagged | +Inquiry |
GLRX-1694R | Recombinant Rhesus Macaque GLRX Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GLRX-5898HCL | Recombinant Human GLRX 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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