| Description : |
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
73.3 kDa |
| AA Sequence : |
MMRLRGSGMLRDLLLRSPAGVSATL RRAQPLVTLCRRPRGGGRPAAGPAA AARLHPWWGGGGWPAEPLARGLSSS PSEILQELGKGSTHPQPGVSPPAAP AAPGPKDGPGETDAFGNSEGKELVA SGENKIKQGLLPSLEDLLFYTIAEG QEKIPVHKFITALKSTGLRTSDPRL KECMDMLRLTLQTTSDGVMLDKDLF KKCVQSNIVLLTQAFRRKFVIPDFM SFTSHIDELYESAKKQSGGKVADYI PQLAKFSPDLWGVSVCTVDGQRHST GDTKVPFCLQSCVKPLKYAIAVNDL GTEYVHRYVGKEPSGLRFNKLFLNE DDKPHNPMVNAGAIVVTSLIKQGVN NAEKFDYVMQFLNKMAGNEYVGFSN ATFQSERESGDRNFAIGYYLKEKKC FPEGTDMVGILDFYFQLCSIEVTCE SASVMAATLANGGFCPITGERVLSP EAVRNTLSLMHSCGMYDFSGQFAFH VGLPAKSGVAGGILLVVPNVMGMMC WSPPLDKMGNSVKGIHFCHDLVSLC NFHNYDNLRHFAKKLDPRREGGDQR VKSVINLLFAAYTGDVSALRRFALS AMDMEQRDYDSRTALHVAAAEGHVE VVKFLLEACKVNPFPKDRWNNTPMD EALHFGHHDVFKILQEYQVQYTPQG DSDNGKENQTVHKNLDGLLSGPTRT RRLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
