Recombinant Human GNLY, His-tagged

• Cat.No.: GNLY-28151TH
• Product Overview: Recombinant full length Human GNLY, isoform 2 with double His Tag, predicted MWt 18.1 kDa including tags.

Specification

• Description: The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Protein length: 130 amino acids
• Conjugation: HIS
• Molecular Weight: 18.100kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Expressed in natural killer and T-cells.
• Form: Lyophilised:It is recommended to reconstitute in sterile Ultra pure water not less than 100μg/ml, which can then be further diluted into other aqueous solutions.Although stable at room temperature for 3 weeks, GNLY-28151TH should be stored desiccated belo
• Purity: >95% by SDS-PAGE
• Storage: Please see Notes section
• Sequences of amino acids: The sequence of the first 25 N-terminal amino acids was determined and was found to be MGSSHHHHHHSSGLVPRGSHMMEGL.
• Sequence Similarities: Contains 1 saposin B-type domain.

Gene Information

• Gene Name: GNLY granulysin [ Homo sapiens ]
• Official Symbol: GNLY
• Synonyms: GNLY; granulysin; LAG2; D2S69E; LAG 2; NKG5; T lymphocyte activation gene 519; TLA519
• Gene ID: 10578
• mRNA Refseq: NM_006433
• Protein Refseq: NP_006424
• MIM: 188855
• Uniprot ID: P22749
• Chromosome Location: 2p12-q11