| Description : |
This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
53.3 kDa |
| AA Sequence : |
MAQHDFAPAWLNFPTPPSSTKSSLN FEKHSENFAWTENRYDVNRRRHNSS DGFDSAIGRPNGGNFGRKEKNGWRT HGRNGTENINHRGGYHGGSSRSRSS IFHAGKSQGLHENNIPDNETGRKED KRERKQFEAEDFPSLNPEYEREPNH NKSLAAGVWEYPPNPKSRAPRMLVI KKGNTKDLQLSGFPVVGNLPSQPVK NGTGPSVYKGLVPKPAAPPTKPTQW KSQTKENKVGTSFPHESTFGVGNFN AFKSTAKNFSPSTNSVKECNRSNSS SPVDKLNQQPRLTKLTRMRTDKKSE FLKALKRDRVEEEHEDESRAGSEKD DDSFNLHNSNSTHQERDINRNFDEN EIPQENGNASVISQQIIRSSTFPQT DVLSSSLEAEHRLLKEMGWQEDSEN DETCAPLTEDEMREFQVISEQLQKN GLRKNGILKNGLICDFKFGPWKNST FKPTTENDDTETSSSDTSDDDDVTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
