Recombinant Human GRID2 Protein, GST-tagged
Cat.No. : | GRID2-5335H |
Product Overview : | Human GRID2 partial ORF ( NP_001501, 908 a.a. - 1007 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named lurcher, in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | DTLPTRQALEQISDFRNTHITTTTF IPEQIQTLSRTLSAKAASGFTFGNV PEHRTGPFRHRAPNGGFFRSPIKTM SSIPYQPTPTLGLNLGNDPDRGTSI |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GRID2 glutamate receptor, ionotropic, delta 2 [ Homo sapiens ] |
Official Symbol : | GRID2 |
Synonyms : | GRID2; glutamate receptor, ionotropic, delta 2; glutamate receptor delta-2 subunit; GluD2; GluR delta 2; GluR-delta-2; gluR delta-2 subunit; MGC117022; MGC117023; MGC117024; |
Gene ID : | 2895 |
mRNA Refseq : | NM_001510 |
Protein Refseq : | NP_001501 |
MIM : | 602368 |
UniProt ID : | O43424 |
Products Types
◆ Recombinant Protein | ||
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GRID2-7261M | Recombinant Mouse GRID2 Protein | +Inquiry |
GRID2-13530H | Recombinant Human GRID2, His-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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