Recombinant Human GRIN1

• Cat.No.: GRIN1-217H
• Product Overview: Recombinant Human GRIN1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Human
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 [ Homo sapiens ]
• Official Symbol: GRIN1
• Gene ID: 2902
• mRNA Refseq: NM_000832.6
• Protein Refseq: NP_000823.4
• MIM: 138249
• UniProt ID: Q05586

Reviews

02/25/2022

This strong track record of excellence further attests to the GRIN1 protein's capability to meet the rigorous demands of research projects.

12/02/2019

Whether measuring analyte concentrations, screening for specific interactions, or monitoring immune responses, this protein's exceptional performance in ELISA experiments is truly commendable.

07/01/2016

Its high quality, reliability, and exceptional performance make it an excellent choice for a wide range of experimental applications.

Q&As

How is the GRIN1 protein involved in neurodegenerative diseases?

Dysregulation of the NMDA receptor, due to GRIN1 mutations, has been linked to neurodegenerative diseases such as Alzheimer's and Parkinson's.

What neurological disorders are associated with GRIN1 mutations?

Disorders such as epilepsy, autism spectrum disorders, and schizophrenia have been linked to GRIN1 mutations.

Is there a genetic test for GRIN1 mutations?

Yes, genetic testing can identify mutations in the GRIN1 gene, which may be helpful in diagnosing certain neurological conditions.

How does the GRIN1 protein contribute to synaptic plasticity?

The NMDA receptor, with GRIN1 as a subunit, is crucial for long-term potentiation, a process underlying memory formation and learning.

Can variations in the GRIN1 gene affect response to antidepressants?

Some studies suggest that genetic variations in GRIN1 may influence an individual's response to antidepressant medications.