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Recombinant Human GRIN1 protein, His-tagged

Cat.No. : GRIN1-1905H
Product Overview : Recombinant Human GRIN1 protein(NP_015566.1)(Arg 19 - Gln 559), fused with His tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : His
Form : PBS, pH7.4
Molecular Mass : 62.4 kDa
Protein Length : Arg 19 - Gln 559
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 [ Homo sapiens ]
Official Symbol : GRIN1
Synonyms : GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; NMDAR1; glutamate [NMDA] receptor subunit zeta-1; GluN1; NMD-R1; glutamate [NMDA] receptor subunit zeta 1; N-methyl-D-aspartate receptor subunit NR1; N-methyl-D-aspartate receptor channel, subunit zeta-1; NR1; MRD8; NMDA1;
Gene ID : 2902
mRNA Refseq : NM_000832
Protein Refseq : NP_000823
MIM : 138249
UniProt ID : Q05586

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is the GRIN1 protein involved in neurodegenerative diseases? 08/10/2022

Dysregulation of the NMDA receptor, due to GRIN1 mutations, has been linked to neurodegenerative diseases such as Alzheimer's and Parkinson's.

What neurological disorders are associated with GRIN1 mutations? 06/09/2022

Disorders such as epilepsy, autism spectrum disorders, and schizophrenia have been linked to GRIN1 mutations.

Is there a genetic test for GRIN1 mutations? 01/12/2021

Yes, genetic testing can identify mutations in the GRIN1 gene, which may be helpful in diagnosing certain neurological conditions.

How does the GRIN1 protein contribute to synaptic plasticity? 03/15/2020

The NMDA receptor, with GRIN1 as a subunit, is crucial for long-term potentiation, a process underlying memory formation and learning.

Can variations in the GRIN1 gene affect response to antidepressants? 02/28/2018

Some studies suggest that genetic variations in GRIN1 may influence an individual's response to antidepressant medications.

Customer Reviews (3)

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Reviews
02/25/2022

    This strong track record of excellence further attests to the GRIN1 protein's capability to meet the rigorous demands of research projects.

    12/02/2019

      Whether measuring analyte concentrations, screening for specific interactions, or monitoring immune responses, this protein's exceptional performance in ELISA experiments is truly commendable.

      07/01/2016

        Its high quality, reliability, and exceptional performance make it an excellent choice for a wide range of experimental applications.

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