Recombinant Human GRK1
Cat.No. : | GRK1-27928TH |
Product Overview : | Recombinant full length Human GRK1 with an N terminal proprietary tag, mol wt: 95 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). |
Protein length : | 563 amino acids |
Molecular Weight : | 95.000kDa |
Source : | Baculovirus infected sf9 cells |
Tissue specificity : | Retina and pineal gland. |
Biological activity : | Specific activity: 4.3 nmol/min/mg |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 1 protein kinase domain.Contains 1 RGS domain. |
Gene Name : | GRK1 G protein-coupled receptor kinase 1 [ Homo sapiens ] |
Official Symbol : | GRK1 |
Synonyms : | GRK1; G protein-coupled receptor kinase 1; rhodopsin kinase , RHOK; rhodopsin kinase; GPRK1; RK; |
Gene ID : | 6011 |
mRNA Refseq : | NM_002929 |
Protein Refseq : | NP_002920 |
MIM : | 180381 |
Uniprot ID : | Q15835 |
Chromosome Location : | 13q34 |
Pathway : | Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Phototransduction, organism-specific biosystem; |
Function : | ATP binding; G-protein coupled receptor kinase activity; nucleotide binding; protein kinase activity; rhodopsin kinase activity; |
Products Types
◆ Recombinant Protein | ||
GRK1-5352H | Recombinant Human GRK1 Protein, GST-tagged | +Inquiry |
GRK1-2364R | Recombinant Rat GRK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Grk1-3311M | Recombinant Mouse Grk1 Protein, Myc/DDK-tagged | +Inquiry |
GRK1-6261C | Recombinant Chicken GRK1 | +Inquiry |
GRK1-2710R | Recombinant Rat GRK1 Protein | +Inquiry |
◆ Lysates | ||
GRK1-5739HCL | Recombinant Human GRK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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