| Description : |
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
66.6 kDa |
| AA Sequence : |
MELENIVANSLLLKARQGGYGKKSG RSKKWKEILTLPPVSQCSELRHSIE KDYSSLCDKQPIGRRLFRQFCDTKP TLKRHIEFLDAVAEYEVADDEDRSD CGLSILDRFFNDKLAAPLPEIPPDV VTECRLGLKEENPSKKAFEECTRVA HNYLRGEPFEEYQESSYFSQFLQWK WLERQPVTKNTFRHYRVLGKGGFGE VCACQVRATGKMYACKKLQKKRIKK RKGEAMALNEKRILEKVQSRFVVSL AYAYETKDALCLVLTIMNGGDLKFH IYNLGNPGFDEQRAVFYAAELCCGL EDLQRERIVYRDLKPENILLDDRGH IRISDLGLATEIPEGQRVRGRVGTV GYMAPEVVNNEKYTFSPDWWGLGCL IYEMIQGHSPFKKYKEKVKWEEVDQ RIKNDTEEYSEKFSEDAKSICRMLL TKNPSKRLGCRGEGAAGVKQHPVFK DINFRRLEANMLEPPFCPDPHAVYC KDVLDIEQFSAVKGIYLDTADEDFY ARFATGCVSIPWQNEMIESGCFKDI NKSESEEALPLDLDKNIHTPVSRPN RGFFYRLFRRGGCLTMVPSEKEVEP KQCTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
