Recombinant Human GRPR Protein, GST-tagged
Cat.No. : | GRPR-5383H |
Product Overview : | Human GRPR full-length ORF ( NP_005305.1, 1 a.a. - 384 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 69.6 kDa |
AA Sequence : | MALNDCFLLNLEVDHFMHCNISSHS ADLPVNDDWSHPGILYVIPAVYGVI ILIGLIGNITLIKIFCTVKSMRNVP NLFISSLALGDLLLLITCAPVDASR YLADRWLFGRIGCKLIPFIQLTSVG VSVFTLTALSADRYKAIVRPMDIQA SHALMKICLKAAFIWIISMLLAIPE AVFSDLHPFHEESTNQTFISCAPYP HSNELHPKIHSMASFLVFYVIPLSI ISVYYYFIAKNLIQSAYNLPVEGNI HVKKQIESRKRLAKTVLVFVGLFAF CWLPNHVIYLYRSYHYSEVDTSMLH FVTSICARLLAFTNSCVNPFALYLL SKSFRKQFNTQLLCCQPGLIIRSHS TGRSTTCMTSLKSTNPSVATFSLIN GNICHERYV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GRPR gastrin-releasing peptide receptor [ Homo sapiens ] |
Official Symbol : | GRPR |
Synonyms : | GRPR; gastrin-releasing peptide receptor; GRP-R; GRP-preferring bombesin receptor; |
Gene ID : | 2925 |
mRNA Refseq : | NM_005314 |
Protein Refseq : | NP_005305 |
MIM : | 305670 |
UniProt ID : | P30550 |
Products Types
◆ Recombinant Protein | ||
GRPR-1802R | Recombinant Rhesus Macaque GRPR Protein, His (Fc)-Avi-tagged | +Inquiry |
GRPR-2377R | Recombinant Rat GRPR Protein, His (Fc)-Avi-tagged | +Inquiry |
GRPR-3946M | Recombinant Mouse GRPR Protein, His (Fc)-Avi-tagged | +Inquiry |
GRPR-7295M | Recombinant Mouse GRPR Protein | +Inquiry |
GRPR-7835H | Recombinant Human GRPR protein, His & T7-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1337 | GRPR U2OS β-Arrestin GPCR Assay Kit | +Inquiry |
Kit-1338 | GRPR Activated GPCR Internalization Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket