Recombinant Human GTF2A2
Cat.No. : | GTF2A2-27775TH |
Product Overview : | Recombinant full length Human GTF2A2 with proprietary tag, Estimated MWt 38kDa. |
- Specification
- Gene Information
- Related Products
Description : | Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al. |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Gene Name : | GTF2A2 general transcription factor IIA, 2, 12kDa [ Homo sapiens ] |
Official Symbol : | GTF2A2 |
Synonyms : | GTF2A2; general transcription factor IIA, 2, 12kDa; general transcription factor IIA, 2 (12kD subunit); transcription initiation factor IIA subunit 2; HsT18745; TFIIA; |
Gene ID : | 2958 |
mRNA Refseq : | NM_004492 |
Protein Refseq : | NP_004483 |
MIM : | 600519 |
Uniprot ID : | P52657 |
Chromosome Location : | 15q21.3 |
Pathway : | Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation and Maturation of mRNA Transcript, organism-specific biosystem; Gene Expression, organism-specific biosystem; |
Function : | TBP-class protein binding; protein binding; protein heterodimerization activity; protein homodimerization activity; transcription coactivator activity; |
Products Types
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GTF2A2-2394R | Recombinant Rat GTF2A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
GTF2A2-2001R | Recombinant Rhesus monkey GTF2A2 Protein, His-tagged | +Inquiry |
GTF2A2-3670C | Recombinant Chicken GTF2A2 | +Inquiry |
◆ Lysates | ||
GTF2A2-5704HCL | Recombinant Human GTF2A2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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