Recombinant Human GTSE1 Protein, GST-tagged

• Cat.No.: GTSE1-4479H
• Product Overview: Human GTSE1 full-length ORF (BAG37928.1, 1 a.a. - 720 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 105.6 kDa
• AA Sequence: MDDPKKEDILLLADEKFDFDLSLSS SSANEDDEVFFGPFGHKERCIAASL ELNNPVPEQPPLPTSESPFAWSPLA GEKFVEVYKEAHLLALHIESSSRNQ AAQAAKPEDPRSQGVERFIQESKLK INLFEKEKEMKKSPTSLKRETYYLS DSPLLGPPVGEPRLLASSPALPSSG AQARLTRAPGPPHSAHALPRESCTA HAASQAATQRKPGTKLLLPRAASVR GRSIPGAAEKPKKEIPASPSRTKIP AEKESHRDVLPDKPAPGAVNVPAAG SHLGQGKRAIPVPNKLGLKKTLLKA PGSTSNLARKSSSGPVWSGASSACT SPAVGKAKSSEFASIPANSSRPLSN ISKSGRMGPAMLRPALPAGPVGASS WQAKRVDVSELAAEQLTAPPSASPT QPQTPEGGGQWLNSSCAWSESSQLN KTRSIRRRDSCLNSKTKVMPTPTNQ FKIPKFSIGDSPDSSTPKLSRAQRP QSCTSVGRVTVHSTPVRRSSGPAPQ SLLSARRVSALPTPASRRCSGLPPM TPKTMPRAVGSPLCVPARRRSSEPR KNSAMRTEPTRESNRKTDSRLVDVS PDRGSPPSRVPQALNFSPEESDSTF SKSTATEVAREEAKPGGDAAPSEAL LVDIKLEPLAVTPDAASQPLIDLPL IDFCDTPEAHVAVGSESRPLIDLMT NTPDMNKNVAKPSPVVGQLIDLSSP LIQLSPEADKENVDSPLLKF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GTSE1 G-2 and S-phase expressed 1 [ Homo sapiens ]
• Official Symbol: GTSE1
• Synonyms: GTSE1; G-2 and S-phase expressed 1; G2 and S phase-expressed protein 1; B99; GTSE 1; protein B99 homolog
• Gene ID: 51512
• mRNA Refseq: NM_016426
• Protein Refseq: NP_057510
• MIM: 607477
• UniProt ID: Q9NYZ3