Recombinant Human GUCY1A2 Protein, GST-tagged

• Cat.No.: GUCY1A2-4488H
• Product Overview: Human GUCY1A2 partial ORF ( NP_000846, 296 a.a. - 401 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Soluble guanylyl (or guanylate) cyclases are heterodimeric enzymes consisting of an alpha subunit, such as alpha-2 (GUCY1A2), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), which are activated by nitric oxide (NO) and which catalyze conversion of GTP to 3-prime, 5-prime-cyclic GMP and pyrophosphate (Harteneck et al., 1991 [PubMed 1683630]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 37.4 kDa
• AA Sequence: CENTNIMKNLPQGTSQVPADLRISI NTFCRAFPFHLMFDPSMSVLQLGEG LRKQLRCDTHKVLKFEDCFEIVSPK VNATFERVLLRLSTPFVIRTKPEAS GSENKD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GUCY1A2 guanylate cyclase 1, soluble, alpha 2 [ Homo sapiens ]
• Official Symbol: GUCY1A2
• Synonyms: GUCY1A2; guanylate cyclase 1, soluble, alpha 2; GUC1A2; guanylate cyclase soluble subunit alpha-2; GC SA2; GCS-alpha-2; GC-SA2
• Gene ID: 2977
• mRNA Refseq: NM_000855
• Protein Refseq: NP_000846
• MIM: 601244
• UniProt ID: P33402