Recombinant Human HABP4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HABP4-1770H
• Product Overview: HABP4 MS Standard C13 and N15-labeled recombinant protein (NP_055097) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress. Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step. Seems to play a role in PML-nuclear bodies formation.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.6 kDa
• AA Sequence: MKGALGSPVAAAGAAMQESFGCVVA NRFHQLLDDESDPFDILREAERRRQ QQLQRKRRDEAAAAAGAGPRGGRSP AGASGHRAGAGGRRESQKERKSLPA PVAQRPDSPGGGLQAPGQKRTPRRG EQQGWNDSRGPEGMLERAERRSYRE YRPYETERQADFTAEKFPDEKPGDR FDRDRPLRGRGGPRGGMRGRGRGGP GNRVFDAFDQRGKREFERYGGNDKI AVRTEDNMGGCGVRTWGSGKDTSDV EPTAPMEEPTVVEESQGTPEEESPA KVPELEVEEETQVQEMTLDEWKNLQ EQTRPKPEFNIRKPESTVPSKAVVI HKSKYRDDMVKDDYEDDSHVFRKPA NDITSQLEINFGNLPRPGRGARGGT RGGRGRIRRAENYGPRAEVVMQDVA PNPDDPEDFPALSTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HABP4 hyaluronan binding protein 4 [ Homo sapiens (human) ]
• Official Symbol: HABP4
• Synonyms: HABP4; hyaluronan binding protein 4; IHABP4; IHABP-4; Ki-1/57; SERBP1L; intracellular hyaluronan-binding protein 4; chromodomain helicase DNA binding protein 3 interacting protein; intracellular antigen detected by monoclonal antibody Ki-1; ki-1/57 intracellular antigen
• Gene ID: 22927
• mRNA Refseq: NM_014282
• Protein Refseq: NP_055097
• MIM: 617369
• UniProt ID: Q5JVS0