| Description : |
Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
72.7 kDa |
| AA Sequence : |
MPRYTVHVRGEWLAVPCQDAQLTVG WLGREAVRRYIKNKPDNGGFTSVDD AHFLVRRCKGLGLLDNEDRLEVALE NNEFVEVVIEGDAMSPDFIPSQPEG VYLYSKYREPEKYIELDGDRLTTED LVNLGKGRYKIKLTPTAEKRVQKSR EVIDSIIKEKTVVYGITTGFGKFAR TVIPINKLQELQVNLVRSHSSGVGK PLSPERCRMLLALRINVLAKGYSGI SLETLKQVIEMFNASCLPYVPEKGT VGASGDLAPLSHLALGLVGEGKMWS PKSGWADAKYVLEAHGLKPVILKPK EGLALINGTQMITSLGCEAVERASA IARQADIVAALTLEVLKGTTKAFDT DIHALRPHRGQIEVAFRFRSLLDSD HHPSEIAESHRFCDRVQDAYTLRCC PQVHGVVNDTIAFVKNIITTELNSA TDNPMVFANRGETISGGNFHGEYPA KALDYLAIGIHELAAISERRIERLC NPSLSELPAFLVAEGGLNSGFMIAH CTAAALVSENKALCHPSSVDSLSTS AATEDHVSMGGWAARKALRVIEHVE QVLAIELLAACQGIEFLRPLKTTTP LEKVYDLVRSVVRPWIKDRFMAPDI EAAHRLLLEQKVWEVAAPYIEKYRM EHIPESRPLSPTAFSLQFLHKKSTK IPESEDLTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
