Recombinant Human HDDC3, His-tagged
Cat.No. : | HDDC3-1528H |
Product Overview : | Recombinant human HDDC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | HDDC3, also known as guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT |
Molecular Mass : | 17.9 kDa (160aa), confirmed by MALDI-TOF |
Protein length : | 1-140aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH LDEVELHFGA QVRRLVEEVT DDKTLPKLER KRLQVEQAPH SSPGAKLVKL ADKLYNLRDL NRCTPEVKIQ MGSEAAQLLE AADFAARKHR QQRRKDPEGT PYINHPIGVA RILTHEAGIT DIVVLQAALL HDTVEDTDTT |
Purity : | > 90% by SDS - PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | HDDC3 HD domain containing 3 [ Homo sapiens (human) ] |
Official Symbol : | HDDC3 |
Synonyms : | HDDC3; MESH1; MGC45386; guanosine-3",5"-bis(diphosphate); 3"-pyrophosphohydrolase MESH1; (ppGpp)ase; OTTHUMP00000180560; OTTHUMP00000180561; metazoan SpoT homolog 1; metazoan SpoT homolog-1; HD domain-containing protein 3; penta-phosphate guanosine-3"-pyrophosphohydrolase |
Gene ID : | 374659 |
mRNA Refseq : | NM_198527 |
Protein Refseq : | NP_940929 |
UniProt ID : | Q8N4P3 |
Chromosome Location : | 15q26.1 |
Pathway : | Purine metabolism |
Function : | guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity; metal ion binding |
Products Types
◆ Recombinant Protein | ||
HDDC3-4657H | Recombinant Human HDDC3 Protein, GST-tagged | +Inquiry |
HDDC3-4096M | Recombinant Mouse HDDC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDDC3-1058H | Recombinant Human HDDC3 Protein, MYC/DDK-tagged | +Inquiry |
Hddc3-3373M | Recombinant Mouse Hddc3 Protein, Myc/DDK-tagged | +Inquiry |
HDDC3-13714H | Recombinant Human HDDC3, GST-tagged | +Inquiry |
◆ Lysates | ||
HDDC3-318HCL | Recombinant Human HDDC3 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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