Recombinant Human Herpesvirus 1 US12 Protein (1-88 aa), His-tagged
Cat.No. : | US12-2571H |
Product Overview : | Recombinant Human Herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) US12 Protein (1-88 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal. Protein Description: Full Length. |
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Description : | Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. pty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes. |
Source : | E. coli |
Species : | Human Herpesvirus 1 |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 13.3 kDa |
Protein length : | 1-88 aa |
AA Sequence : | MSWALEMADTFLDTMRVGPRTYADV RDEINKRGREDREAARTAVHDPERP LLRSPGLLPEIAPNASLGVAHRRTG GTVTDSPRNPVTR |
Purity : | > 85% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | US12 TAP transporter inhibitor ICP47 [ Human alphaherpesvirus 1 (Herpes simplex virus type 1) ] |
Official Symbol : | US12 |
Synonyms : | US12; |
Gene ID : | 2703441 |
Protein Refseq : | YP_009137148 |
UniProt ID : | P03170 |
Products Types
◆ Recombinant Protein | ||
US12-1619H | Recombinant Human Herpesvirus 1 US12 Protein (1-88 aa), His-tagged | +Inquiry |
US12-4087H | Recombinant Herpes simplex virus type 2 US12 protein, His-KSI-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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