Recombinant Human HIPK3 Protein (P161-N562), GST tagged
Cat.No. : | HIPK3-1129H |
Product Overview : | Recombinant Human GST-TEV-GG-HIPK3(P161-N562) Protein was expressed in Insect cell. |
- Specification
- Gene Information
- Related Products
Description : | Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE). |
Source : | Insect cell |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Protein Length : | P161-N562 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | HIPK3 homeodomain interacting protein kinase 3 [ Homo sapiens (human) ] |
Official Symbol : | HIPK3 |
Synonyms : | HIPK3; homeodomain interacting protein kinase 3; homeodomain-interacting protein kinase 3; DYRK6; FIST3; PKY; YAK1; ANPK; FIST; homolog of protein kinase YAK1; fas-interacting serine/threonine-protein kinase; androgen receptor-interacting nuclear protein kinase; |
Gene ID : | 10114 |
mRNA Refseq : | NM_001048200 |
Protein Refseq : | NP_001041665 |
MIM : | 604424 |
UniProt ID : | Q9H422 |
Products Types
◆ Recombinant Protein | ||
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HIPK3-5428H | Recombinant Human Homeodomain Interacting Protein Kinase 3, His-tagged | +Inquiry |
HIPK3-1128H | Recombinant Human HIPK3 Protein (P161-N562), Tag Free | +Inquiry |
Hipk3-1623M | Recombinant Mouse Hipk3 Protein, His-tagged | +Inquiry |
HIPK3-2501R | Recombinant Rat HIPK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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