Recombinant Human Histone Deacetylase 3, GST-tagged
Cat.No. : | HDAC3-1591H |
Product Overview : | Full-length recombinant human HDAC3 was expressed by baculovirus in Sf9 insect cells using a C-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HDAC3-1591H |
Description : | HDAC3 or Histone deacetylase 3 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex that represses transcription when tethered to a promoter. HDAC3 may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. HDAC3 can also down-regulate p53 function and thus modulate cell growth and apoptosis. |
Applications : | HDAC Assay; Western Blot |
Molecular Weight : | 83 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Purity : | >70% |
Concentration : | 0.1 ug/ul |
Specific Activity : | 125 RLU/min/ng |
Sequences : | Full length |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Cell cycle; Diabetes pathways; Fatty acid, triacylglycerol; Metabolism of lipids and lipoproteins; Regulation of retinoblastoma protein; Retinoic acid receptors-mediated signaling; Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Class II; Signalling by NGF; Transcriptional Regulation of White Adipocyte Differentiation; Validated targets of C-MYC transcriptional repression; p75 NTR receptor-mediated signaling; p75NTR negatively regulates cell cycle via SC1 |
Gene Name : | HDAC3 histone deacetylase 3 [ Homo sapiens ] |
Official Symbol : | HDAC3 |
Synonyms : | HDAC3; histone deacetylase 3; HD3; RPD3; RPD3-2; histone deacetylase 3; SMAP45; OTTHUMP00000160029 |
Gene ID : | 8841 |
mRNA Refseq : | NM_003883 |
Protein Refseq : | NP_003874 |
MIM : | 605166 |
UniProt ID : | O15379 |
Chromosome Location : | 5q31.1-q31 |
Function : | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; transcription factor binding; chromatin binding; DNA binding; protein deacetylase activity; transcription corepressor activity |
Products Types
◆ Recombinant Protein | ||
HDAC3-3099H | Recombinant Human HDAC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC3-550H | Recombinant Human HDAC3 Protein (1-428 aa), His-SUMO-tagged | +Inquiry |
Hdac3-1103M | Recombinant Mouse Hdac3 Protein, MYC/DDK-tagged | +Inquiry |
HDAC3-1054H | Recombinant Human HDAC3 Protein, MYC/DDK-tagged | +Inquiry |
HDAC3-2235H | Recombinant Human HDAC3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
HDAC3-572HCL | Recombinant Human HDAC3 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2254 | HDAC3 Activity Fluorometric Assay Kit | +Inquiry |
Kit-1739 | HDAC3 Kinetic Assay Kit | +Inquiry |
Kit-2282 | HDAC3 Immunoprecipitation (IP) & Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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