Recombinant Human HSD11B1 Protein, His-tagged
Cat.No. : | HSD11B1-019H |
Product Overview : | Recombinant Human HSD11B1 protein with a N-terminal His-tag was expressed in E.coli |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 31.4 kDa |
Purity : | ≥75% estimated by SDS-PAGE |
Unit Definition : | One unit is defined as the amount of enzyme required to produce 1 nmol of cortisol per minute at 37 centigrade in 50 mM sodium phosphate buffer, pH 7.6, containing 100 mM sodium chloride, using 40 µM cortisone as substrate, and 500 µM NADPH. |
Stability : | ≥ 6 months |
Storage : | -80 centigrade |
Storage Buffer : | 50 mM sodium phosphate buffer, pH 7.6, containing 100 mM sodium chloride and 20% glycerol |
Shipping : | Dry ice in continental US, may vary elsewhere. |
Gene Name : | HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 [ Homo sapiens (human) ] |
Official Symbol : | HSD11B1 |
Synonyms : | HSD11B1; hydroxysteroid 11-beta dehydrogenase 1; HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1; corticosteroid 11-beta-dehydrogenase isozyme 1; short chain dehydrogenase/reductase family 26C member 1; EC 1.1.1.146 |
Gene ID : | 3290 |
mRNA Refseq : | NM_001206741 |
Protein Refseq : | NP_001193670 |
MIM : | 600713 |
UniProt ID : | P28845 |
Products Types
◆ Recombinant Protein | ||
HSD11B1-0319H | Recombinant Human HSD11B1 Protein (M1-K292), Tag Free | +Inquiry |
HSD11B1-1099H | Recombinant Human HSD11B1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HSD11B1-065H | Active Recombinant Human HSD11B1 Protein, His-tagged | +Inquiry |
HSD11B1-2256H | Recombinant Human HSD11B1 Protein, His-tagged | +Inquiry |
HSD11B1-0320H | Recombinant Human HSD11B1 Protein (M1-K292), His/Strep tagged | +Inquiry |
◆ Lysates | ||
HSD11B1-5380HCL | Recombinant Human HSD11B1 293 Cell Lysate | +Inquiry |
HSD11B1-5381HCL | Recombinant Human HSD11B1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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