Recombinant Human HSD17B4 protein, GST-tagged
Cat.No. : | HSD17B4-111H |
Product Overview : | Recombinant Human HSD17B4(1 a.a. - 736 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 107.36 kDa |
Protein length : | 1 a.a. - 736 a.a. |
AA Sequence : | MGSPLRFDGRVVLVTGAGAGLGRAY ALAFAERGALVVVNDLGGDFKGVGK GSLAADKVVEEIRRRGGKAVANYDS VEEGEKVVKTALDAFGRIDVVVNNA GILRDRSFARISDEDWDIIHRVHLR GSFQVTRAAWEHMKKQKYGRIIMTS SASGIYGNFGQANYSAAKLGLLGLA NSLAIEGRKSNIHCNTIAPNAGSRM TQTVTPEDLVEALKPEYVAPLVLWL CHESCEENGGLFEVGAGWIGKLRWE RTLGAIVRQKNHPMTPEAVKANWKK ICDFENASKPQSIQESTGSIIEVLS KIDSEGGVSANHTSRATSTATSGFA GAIGQKLPPFSYAYTELEAIMYALG VGASIKDPKDLKFIYEGSSDFSCLP TFGVIIGQKSMMGGGLAEIPGLSIN FAKVLHGEQYLELYKPLPRAGKLKC EAVVADVLDKGSGVVIIMDVYSYSE KELICHNQFSLFLVGSGGFGGKRTS DKVKVAVAIPNRPPDAVLTDTTSLN QAALYRLSGDRNPLHIDPNFASLAG FDKPILHGLCTFGFSARRVLQQFAD NDVSRFKAVKARFAKPVYPGQTLQT EMWKEGNRIHFQTKVQETGDIVISN AYVDLAPTSGTSAKTPSEGGKLQST FVFEEIGRRLKDIGPEVVKKVNAVF EWHITKGGNIGAKWTIDLKSGSGKV YQGPAKGAADTTIILSDEDFMEVVL GKLDPQKAFFSGRLKARGNIMLSQK LQMILKDYAKL |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 [ Homo sapiens ] |
Official Symbol : | HSD17B4 |
Synonyms : | HSD17B4; hydroxysteroid (17-beta) dehydrogenase 4; peroxisomal multifunctional enzyme type 2; 3 alpha; 7 alpha; 12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase; 17 beta HSD IV; 17 beta hydroxysteroid dehydrogenase 4; 17beta estradiol dehydrogenase type IV; beta hydroxyacyl dehydrogenase; beta keto reductase; D 3 hydroxyacyl CoA dehydratase; D bifunctional protein; peroxisomal; DBP; MFE 2; peroxisomal multifunctional protein 2; SDR8C1; short chain dehydrogenase/reductase family 8C; member 1; 17-beta-HSD 4; 17-beta-HSD IV; beta-keto-reductase; multifunctional protein 2; beta-hydroxyacyl dehydrogenase; D-3-hydroxyacyl-CoA dehydratase; D-bifunctional protein, peroxisomal; 17-beta-hydroxysteroid dehydrogenase 4; 17beta-estradiol dehydrogenase type IV; short chain dehydrogenase/reductase family 8C, member 1; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; MFE-2; MPF-2; |
Gene ID : | 3295 |
mRNA Refseq : | NM_000414 |
Protein Refseq : | NP_000405 |
MIM : | 601860 |
UniProt ID : | P51659 |
Chromosome Location : | 5q2 |
Pathway : | Beta-oxidation of pristanoyl-CoA, organism-specific biosystem; Beta-oxidation of very long chain fatty acids, organism-specific biosystem; Bile acid and bile salt metabolism, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, conserved biosystem; |
Function : | 3-hydroxyacyl-CoA dehydrogenase activity; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; estradiol 17-beta-dehydrogenase activity; isomerase activity; long-chain-enoyl-CoA hydratase activity; lyase activity; nucleotide binding; oxidoreductase activity; sterol binding; sterol transporter activity; |
Products Types
◆ Recombinant Protein | ||
HSD17B4-1417H | Recombinant Human HSD17B4 Protein (1-736 aa), His-tagged | +Inquiry |
HSD17B4-1106H | Recombinant Human HSD17B4 Protein, His (Fc)-Avi-tagged | +Inquiry |
HSD17B4-4336M | Recombinant Mouse HSD17B4 Protein, His (Fc)-Avi-tagged | +Inquiry |
HSD17B4-2583R | Recombinant Rat HSD17B4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Hsd17b4-1180M | Recombinant Mouse Hsd17b4 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
HSD17B4-5373HCL | Recombinant Human HSD17B4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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