Recombinant Human Human PIK3CA, His-tagged
Cat.No. : | PIK3R1-29688TH |
Product Overview : | Recombinant full length Human PI 3 Kinase p110alpha mutant + PI 3 kinase p85 alpha coexpressed by baculovirus in Sf9 insect cells with N terminal His tag on both proteins. Molecular weights: 111kDa and 86kDa; |
- Specification
- Gene Information
- Related Products
Description : | Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. |
Conjugation : | HIS |
Biological activity : | The specific activity of PI 3 Kinase p110alpha + PI 3 kinase p85 alpha was determined to be 50 nm/min/mg as per activity assay protocol. |
Form : | Liquid |
Storage buffer : | Preservative: 150mM ImidazoleConstituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Gene Name : | PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) [ Homo sapiens ] |
Official Symbol : | PIK3R1 |
Synonyms : | PIK3R1; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); phosphatidylinositol 3-kinase regulatory subunit alpha; GRB1; p85; p85 ALPHA; |
Gene ID : | 5295 |
mRNA Refseq : | NM_001242466 |
Protein Refseq : | NP_001229395 |
MIM : | 171833 |
Uniprot ID : | P27986 |
Chromosome Location : | 5q13.1 |
Pathway : | 3-phosphoinositide biosynthesis, conserved biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; |
Function : | 1-phosphatidylinositol binding; ErbB-3 class receptor binding; insulin binding; insulin receptor binding; insulin receptor substrate binding; |
Products Types
◆ Recombinant Protein | ||
PIK3R1-3252R | Recombinant Rhesus Macaque PIK3R1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIK3R1-4934H | Recombinant Human PIK3R1 Protein, His-tagged | +Inquiry |
Pik3r1-4865M | Recombinant Mouse Pik3r1 Protein, Myc/DDK-tagged | +Inquiry |
PIK3R1-4123R | Recombinant Rat PIK3R1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIK3R1-3434R | Recombinant Rhesus monkey PIK3R1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PIK3R1-3185HCL | Recombinant Human PIK3R1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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