Recombinant Human IA2, His-tagged
| Cat.No. : | IA2-01HFL |
| Product Overview : | Recombinant Human IA2(NP_001186692.1), fused to His-tag, was expressed in insect cell. |
- Specification
- Gene Information
- Related Products
| Description : | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants. |
| Source : | Insect cell |
| Species : | Human |
| Tag : | His |
| Form : | PBS, pH 7.4. |
| Molecular Mass : | The protein has a calculated MW of 102 kDa. |
| AA Sequence : | HHHHHHMSSRPGGCSAVSAHGCLFD RRLCSHLEVCIQDGLFGQCQVGVGQ ARPLLQVTSPVLQRLQGVLRQLMSQ GLSWHDDLTQYVISQEMERIPRLRP PEPRPRDRSGLAPKRPGPAGELLLQ DIPTGSAPAAQHRLPQPPVGKGGAG ASSSLSPLQAELLPPLLEHLLLPPQ PPHPSLSYEPALLQPYLFHQFGSRD GSRVSEGSPGMVSVGPLPKAEAPAL FSRTASKGIFGDHPGHSYGDLPGPS PAQLFQDSGLLYLAQELPAPSNARV PRLPEQGSSSRAEDSPEGYEKEGLG DRGEKPASPAVQPDAALQRLAAVLA GYGVELRQLTPEQLSTLLTLLQLLP KGAGRNPGGVVNVGADIKKTMEGPV EGRDTAELPARTSPMPGHPTASPTS SEVQQVPSPVSSEPPKAARPPVTPV LLEKKSPLGQSQPTVAGQPSARPAA EEYGYIVTDQKPLSLAAGVKLLEIL AEHVHMSSGSFINISVVGPALTFRI RHNEQNLSLADVTQQAGLVKSELEA QTGLQILQTGVGQREEAAAVLPQTA HSTSPMRSVRQHARQQDKERLAALG PEGAHGDTTFEYQDLCRQHMATKSL FNRAEGPPEPSRVSSVSSQFSDAAQ ASPSSHSSTPSWCEEPAQANMDIST GHMILAYMEDHLRNRDRLAKEWQAL CAYQAEPNTCATAQGEGNIKKNRHP DFLPYDHARIKLKVESSPSRSDYIN ASPIIEHDPRMPAYIATQGPLSHTI ADFWQMVWESGCTVIVMLTPLVEDG VKQCDRYWPDEGASLYHVYEVNLVS EHIWCEDFLVRSFYLKNVQTQETRT LTQFHFLSWPAEGTPASTRPLLDFR RKVNKCYRGRSCPIIVHCSDGAGRT GTYILIDMVLNRMAKGVKEIDIAAT LEHVRDQRPGLVRSKDQFEFALTAV AEEVNAILKALPQ |
| Purity : | >90%, by SDS-PAGE |
| Storage : | Store it under sterile conditions at -20 to -80 ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : | 0.03 mg/ml |
| Gene Name : | PTPRN protein tyrosine phosphatase receptor type N [ Homo sapiens (human) ] |
| Official Symbol : | IA2 |
| Synonyms : | IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP |
| Gene ID : | 5798 |
| mRNA Refseq : | NM_001199763.2 |
| Protein Refseq : | NP_001186692.1 |
| MIM : | 601773 |
| UniProt ID : | Q16849 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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