Recombinant Human ICAM2, His-tagged
Cat.No. : | ICAM2-152H |
Product Overview : | ICAM2, 22-223aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. Recombinant human ICAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 24.8 kDa (225aa) confirmed by MALDI-TOF |
Protein length : | 22-223aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSSDEKVFE VHVRPKKLAV EPKGSLEVNC STTCNQPEVG GLETSLDKIL LDEQAQWKHY LVSNISHDTV LQCHFTCSGK QESMNSNVSV YQPPRQVILT LQPTLVAVGK SFTIECRVPT VEPLDSLTLF LFRGNETLHY ETFGKAAPAP QEATATFNST ADREDGHRNF SCLAVLDLMS RGGNIFHKHS APKMLEIYEP VSDSQ |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | ICAM2 intercellular adhesion molecule 2 [ Homo sapiens ] |
Official Symbol : | ICAM2 |
Synonyms : | ICAM2; intercellular adhesion molecule 2; CD102; ICAM-2; |
Gene ID : | 3384 |
mRNA Refseq : | NM_000873 |
Protein Refseq : | NP_000864 |
MIM : | 146630 |
UniProt ID : | P13598 |
Chromosome Location : | 17q23-q25 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; |
Function : | integrin binding; |
Products Types
◆ Recombinant Protein | ||
ICAM2-603H | Active Recombinant Human ICAM2 protein(Met1-Gln223), His&hFc-tagged | +Inquiry |
ICAM2-797H | Recombinant Human ICAM2 Protein, MYC/DDK-tagged | +Inquiry |
ICAM2-1037M | Recombinant Mouse ICAM2 protein(Met 1-Gln 222) | +Inquiry |
ICAM2-293H | Recombinant Human ICAM2 Protein, His-tagged | +Inquiry |
ICAM2-059H | Recombinant Human ICAM2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ICAM2-2427HCL | Recombinant Human ICAM2 cell lysate | +Inquiry |
ICAM2-1087MCL | Recombinant Mouse ICAM2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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